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Trying to Conceive at 37: What are the Chances of My Baby Having Down Syndrome?

Dr Nandita

Dr Nandita Palshetkar  |52 Answers  |Ask -

Gynaecologist, IVF expert - Answered on Dec 02, 2024

Dr Nandita Palshetkar is the medical director of Bloom IVF.
She is a pioneer in ICSI, laser hatching, spindle view, oocyte and embryo freezing, IMSI, in vivo vaginal culture, metabolomics, embryoscope and spindle check technologies.
With over 30 years of experience, Dr Nandita is managing 10 centres across India.
She has written over 100 papers, edited 25 books and given over 1,000 lectures and speeches.
She has also won several prestigious awards, including the Dronacharya Award (2021), the Bharat Gaurav Award at the House of Commons in London (2014) and the Inspiring Gynaecologists of India (2018) to name a few.
Dr Nandita completed her MBBS from Grant Medical College and Sir J J Hospital, Mumbai, and her MD in obstetrics and gynaecology from Mumbai University."... more
Asked by Anonymous - Nov 28, 2024Hindi
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What are the chances of your baby having Down syndrome if you conceive after 35? My husband is 39 and I am 37. We are planning to have a baby but I am also worried about these complications. Please help.

Ans: Considering your age 37 and husband 39 and planning to have a baby
The chance of having a child with Down syndrome increases with the mother's age:
Age 25: The chance is about 1 in 1,200
Age 35: The chance is about 1 in 400
Age 40: The chance is about 1 in 100
Age 45: The chance is about 1 in 30
If you're over 35 and thinking about getting pregnant, you can:
Get genetic counseling to learn more about your risk
Get regular checkups
Eat a variety of healthy foods
Get regular exercise and plenty of rest
Avoid smoking, vaping, drinking alcohol, and using cannabis or other drugs
To start folic acid (vit B6 and B 12) and DHA 3 months prior to conception.
Learn about prenatal testing for chromosomal conditions like your gynae will perform serial ultrasound at different trimesters like NT SCAN, anomaly scan, fetal 2 D echo and blood markers like dual marker and NIPT to rule out any form of congenital anomalies.
DISCLAIMER: The answer provided by rediffGURUS is for informational and general awareness purposes only. It is not a substitute for professional medical diagnosis or treatment.
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Asked by Anonymous - Oct 10, 2024Hindi
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I am 41 and my husband is 45. After 3 miscarriages, we are having our first baby after 10 years of marriage. I am scared and anxious because of my age. Will there be any complications to the baby? My gynaec has advised some genetic tests but I am worried about the results. How can we ensure to have a safe delivery for a healthy baby?
Ans: Since you are 41 years old, had three previous miscarriages, and were conceiving after ten years, there were certain measures that needed to be taken.
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Asked by Anonymous - Feb 08, 2025
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Me and my girlfriend we both are in relationship from about last 2 years (almost). After such a long time I got to know that she had 2 relationships before me that too she didn't told I got to know it by third person she was sexually involved too (not intercourse but yes other things with one of them)... When I asked her that why you didn't told anything to me before she said she was scared that if she'll tell it to me so I'll leave her and she really did not wanted that... She was scared to loose me. And she was still in contact with that guy and when I asked her that why you were still in contact with him (it's been around 3 years they got separated) so she says that she is like that only... She can't deny anyone because of her soft hearted nature but she did not had any feelings for him. She also said that once she even went to meet him when he requested to meet and also on the same she claims that her soft hearted nature has done that she wasn't able to deny. I loved her too much but now all these things are hurting me like anything. (She is my first relationship before her i never had anyone)
Ans: Dear Anonymous,
I understand that you are hurt and the complexities of the hearts might be difficult sometimes to grasp. The first reason for your sorrow, her past relationship, and the fact that she was physically intimate with them is not completely justifiable. Though I understand that you feel hurt because she did not disclose it to you, still it should not matter so much as to ruin your present relationship. And whether she will open up about such sensitive details is actually up to her. It has nothing to do with how much she loves you or trusts you. Please understand that.

Now coming to the next thing, the fact that she is still in touch with them and has even met one of them, that is slightly concerning. It would have been okay if she did that openly- please understand that I am not saying she should have asked for your permission, but rather discuss the same with you. Moreover, in a relationship, it is also important to understand how much your partner is comfortable with- goes for both men and women. If you are uncomfortable with her relationship with her exes, she should consider that. I would have said the same if the table was turned. I suggest you have a clear conversation with her and express how you feel about this situation- depending on how she reacts and how the conversation goes, you both can think about the next step.

Hope this helps.

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