Can I Take PPI Long-Term Even on an Empty Stomach?

I am 52 years old having health issue like excessive hunger and weight loss. I have met Diabetologist and my HbA1C is 6.0. Doctor advised me to takeoioz 15 mg daily on in the afternoon after food. I am yet to start. I have been facing this problem for last 6 - 7 years. I have seen Gastroenterologist as well and as advised by the Doctor i have undergone Endoscopy. However, the same was normal. My problem is not yet solved. Everyday when I wake up in the morning I am having the feeling of complete empty stomach and the weight loss. Through out the day I will have feeling of emptiness in the stomach even after eating. I do not have problem of digestion, but I have excess gas. Please suggest me. With regards,

Hi my name is arun, i am suffering from GERD like related issues from last 6 years and my throat ear pains sometime and my tip of tongue gets tingling issue and i generate lots of gas. I dont have stomach pain or any other issue. i am taking PPI for last 5 years, should i stop that?

Good Morning Doctor, I have been suffering from GERD ( diagnosed by doctor) from last many years and taking continuous treatment from allopathy, homeopathy and even ayurvedic also but not getting permanent relief . I take home made food regularly without oil and spices. I do exercise regularly. Despite of all these, I have to take SOMPRAZ L capsule regularly. Doctors have conducted many tests , such as endoscopy, colonoscopy, USG and many more but nothing can be diagnosed. They are asking for CT Scan of whole abdomen ( AIG, Hyderabad) . Would it be last test? Can SOMPRAZ - L be taken regularly? Kindly suggest best remedy to cure . Still I feel stomach like balloon, burping, spasm, burning sensation in from mouth to stomach. Kindly advise good medicine and its best treatment in India.

Is GERD medications is life long medicine. Because when I stopped PPI after few days I feel bloated and feeling discomfort in stomach?